Response to Professor Rumboldt’s reaction to our letter on hydroxyethyl starch use in managing aluminium phosphide poisoning

Hydroxyethyl starch should not be used to manage severe aluminium phosphide poisoning.

In the Archives January issue (1), I have read with interest and surprise a letter by Marashi and Nasrabadi concerning the use of hydroxyethyl starch (HES, hetastarch; best known under the registered name Plasmasteril) to treat severe aluminium phosphide (AlP) poisoning. At the current level of scientific evidence such a claim seems unacceptable. Aluminium phosphide poisoning (the compound is c...

Effect of hydroxyethyl starch on acidosis in patients with aluminum phosphide poisoning

Background: Given the fact that various studies have reported the positive effects of hydroxyethyl starch therapy in controlling shock, this study aimed to compare the effects of hydroxyethyl starch on modifying acidosis and treating patients with aluminum phosphide poisoning. Methods: This was a randomized clinical trial that was conducted on 60 patients with aluminum phosphide poisoning. We ...

Fatal aluminium phosphide poisoning

Aluminium phosphide (AlP) is a cheap solid fumigant and a highly toxic pesticide which is commonly used for grain preservation. AlP has currently aroused interest with a rising number of cases in the past four decades due to increased use for agricultural and non-agricultural purposes. Its easy availability in the markets has increased also its misuse for committing suicide. Phosphine inhibits ...

Aluminium phosphide poisoning.

We describe a lethal poisoning in a healthy woman caused by deliberate ingestion of aluminium phosphide (AlP), a pesticide used to kill rodents and insects. Toxicity of AlP and review of cases reported to the National Poisons Information Service (London) 1997-2003 are discussed.

Aluminium Phosphide Poisoning